The Best Science Movies of All Time (in our opinion)

Okay, so there aren’t a ton of movies about being in the laboratory and it's even more rare that they accurately portray how science actually works. However, there are many that are laboratory adjacent. Anyway, who doesn’t like to see Matt Damon or Julia Roberts or yes, Jeff Goldblum in (or around) a laboratory. Let’s get to it.

Scene from Contagion (2011)

1.      Contagion (2011)

Hitting a little too close to home, "Contagion" is a chilling, realistic depiction of a global pandemic caused by a novel virus, eerily prescient in light of recent events. The film follows the rapid spread of the virus and the ensuing efforts by public health officials and scientists to contain it. Directed by Steven Soderbergh, it features a star-studded cast and meticulously portrays the science behind epidemiology, vaccine development, and crisis management. The movie’s attention to detail in depicting the medical and societal impact of a pandemic has been widely praised. It serves as a stark reminder of the vulnerability of global health systems and the importance of scientific preparedness. It also helps to have a lights-out cast.

2.      And the Band Played On (1993)

Based on the book by Randy Shilts, "And the Band Played On" is a powerful depiction of the early years of the AIDS epidemic. The film highlights the struggles of researchers, particularly those at the Centers for Disease Control and Prevention, as they race against time to identify the mysterious virus. It portrays the bureaucratic and political challenges that hindered scientific progress, emphasizing the importance of public health awareness. With an ensemble cast and a gripping narrative, the movie provides a compelling look into the scientific and social complexities of epidemic response. It remains a significant film in illustrating the intersection of science, politics, and human lives.

3.      The Constant Gardener (2005)

Adapted from the G.O.A.T. of the spy genre John le Carré’s novel, "The Constant Gardener" is a thriller that delves into the dark side of the pharmaceutical industry. The story follows a British diplomat in Kenya who uncovers a conspiracy involving drug trials on the local population, leading to tragic consequences. The film effectively combines elements of romance, mystery, and social critique, with stunning visuals of Africa’s landscapes. It raises ethical questions about medical research, corporate greed, and the exploitation of vulnerable communities. The movie’s portrayal of the pursuit of truth amidst danger and deception makes it both thought-provoking and suspenseful.

4.      The Immortal Life of Henrietta Lacks (2017)

This biographical drama, based on Rebecca Skloot’s book, tells the story of Henrietta Lacks, whose cancer cells were taken without her consent and used to create the first immortal human cell line. The film explores the ethical implications of this scientific breakthrough, as well as the impact on Lacks’ family. Oprah Winfrey stars as Lacks’ daughter, who seeks to uncover the truth about her mother’s legacy and the exploitation of her cells by the medical community. The movie brings attention to issues of consent, race, and the ethics of medical research. It’s a powerful reminder of the human stories behind scientific progress and the need for ethical standards in medical practice. The book version is probably a little better.

Scene from Gattaca (1997)

5.      Gattaca (1997)

This one is more sci-fi than science, but "Gattaca" is a thought-provoking science fiction film that delves into the ethical and societal implications of genetic engineering. Set in a future where eugenics determines social status, the movie follows Vincent Freeman, a man conceived naturally, as he struggles to overcome the genetic discrimination that limits his opportunities. The film explores themes of identity, ambition, and the moral dilemmas of manipulating human genetics. With its sleek visual style and intelligent narrative, "Gattaca" raises important questions about the potential consequences of genetic advancements in medicine and society. It remains a poignant commentary on the human spirit’s ability to transcend biological limitations.

6.      Outbreak (1995)

A modern lab classic, "Outbreak" is a tense medical thriller that dramatizes the spread of a deadly, Ebola-like virus in a small American town. Directed by Wolfgang Petersen, the film stars Dustin Hoffman as a U.S. Army virologist racing to prevent the virus from becoming a global catastrophe. The movie combines action, suspense, and a portrayal of the scientific challenges in controlling infectious diseases. While some aspects are dramatized for cinematic effect, the film raises awareness of the real threats posed by emerging viruses and the importance of coordinated public health responses. It remains a popular and engaging depiction of the battle against viral epidemics.

7.      Awakenings (1990)

"Awakenings," based on Oliver Sacks’ memoir, tells the true story of a neurologist who discovers a drug that temporarily revives patients from a catatonic state. Robin Williams stars as Dr. Malcolm Sayer, whose groundbreaking treatment offers hope to patients who have been unresponsive for decades. The film poignantly explores themes of hope, loss, and the transient nature of medical miracles. With powerful performances by Williams and Robert De Niro, the movie emphasizes the human side of medical research and the profound impact of neurological discoveries. "Awakenings" is both a celebration of medical advances and a meditation on the limits of medicine.

8.      The Andromeda Strain (1971)

Based on Michael Crichton’s novel, "The Andromeda Strain" is a classic science fiction thriller about a team of scientists working to contain a deadly extraterrestrial microorganism. The film’s detailed depiction of scientific processes, including laboratory work, biological containment, and analysis, sets it apart from other sci-fi movies of its time. The tension builds as the scientists race to prevent the spread of the alien pathogen, showcasing both the potential and the dangers of scientific discovery. Its methodical pace and attention to detail have made it a cult favorite among fans of both science fiction and medical thrillers. The movie remains a fascinating exploration of the intersection of science and fiction.

9.      Flatliners (1990)

"Flatliners" explores the boundaries of life and death as a group of medical students experiment with near-death experiences. Directed by Joel Schumacher, the film follows the students as they take turns stopping their hearts to explore the afterlife, only to face terrifying consequences. The movie is a mix of horror, science fiction, and medical drama, examining the psychological and ethical implications of their experiments. With a strong cast, including Kiefer Sutherland and Julia Roberts, "Flatliners" raises questions about the pursuit of knowledge at any cost. The film’s exploration of the unknown and its consequences is both thrilling and thought-provoking.

10.  Lorenzo's Oil (1992)

"Lorenzo’s Oil" is a true story about a couple’s relentless quest to find a cure for their son’s rare and fatal neurological disorder, adrenoleukodystrophy (ALD). The film highlights the challenges they face as they navigate the complexities of medical research, often clashing with the medical establishment. Nick Nolte and Susan Sarandon deliver powerful performances as the determined parents, making the story both heartbreaking and inspiring. The movie sheds light on the often arduous journey of medical discovery and the impact of patient advocacy in driving research forward. "Lorenzo’s Oil" is a moving testament to the power of hope and the resilience of the human spirit.

Scene from The Fly (1986)

Bonus pick: The Fly (1986)

Love it, hate it, or just be weirded out by it. "The Fly," directed by David Cronenberg, is a horror-science fiction film that explores the catastrophic consequences of a scientist’s experiment gone wrong. The story follows Seth Brundle, a brilliant but reckless scientist, who accidentally merges his DNA with that of a fly during a teleportation experiment. As Brundle slowly transforms into a human-fly hybrid, the movie delves into themes of identity, the dangers of unchecked scientific experimentation, and the terrifying possibilities of genetic mutation. Jeff Goldblum’s performance as Brundle is both tragic and horrifying, making "The Fly" a compelling exploration of the boundaries of scientific inquiry and the potential perils of human ambition. The film is a stark reminder of the ethical considerations that must accompany scientific progress. It was also frightening if you watched it as a kid.

Classic pick: Frankenstein (1931)

Frankenstein," directed by James Whale, is a classic horror film based on Mary Shelley’s novel, exploring the consequences of unchecked scientific ambition. The story follows Dr. Henry Frankenstein, a scientist obsessed with creating life, who assembles a living being from parts of dead bodies. The creature, brought to life through a dramatic experiment, becomes a tragic figure as it struggles with its own existence and the fear and rejection it faces from society. The film raises profound ethical questions about the limits of scientific experimentation, the responsibilities of a creator, and the nature of humanity. "Frankenstein" remains a seminal work in both cinema and literature, serving as a cautionary tale about the dangers of playing God. For a new take, check out Yorgos Lanthimos’s “Poor Things” (2023).